Cephradine NEW
| Price | $29 |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Cephradine | CAS No.: 38821-53-3 |
| Purity: mixture | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Cephradine |
| Description | Cephradine (Anspor) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity. |
| Cell Research | Cells Are seeded in six-well culture plates (9.6 cm2, growth area) at a density of 105 cells/cm2. At 2 days postseeding, the medium is removed and cells are washed twice with pH 6.0 uptake buffer. Independent studies are performed for each drug solution at 1 mg/mL made in pH 6.0 uptake buffer. At each time point (10, 20, 30, 45, 60, 90 min), drug solution is removed and cells are washed three times with ice-cold pH 6.0 uptake buffer. One milliliter of Milli-Q water is added to each well and incubated for 30 min at 25 °C. Cells are harvested and sonicated for 1-2 min. ZnSO4 solution (8%, 200 mL) is added to the cell lysate, vortexed rigorously, and centrifuged for 5 min at 3000 rpm. After filtration of the supernatant through a membrane filter (0.45 mm), samples are analyzed by HPLC. (Only for Reference) |
| In vivo | Cephradine has a low order of acute, subacute, and chronic oral toxicity, and acute and subacute parenteral toxicity. After daily intravenous doses of cephradine has been given to monkeys for 2 weeks, these animals show no signs of nephrotoxicity. Cephradine does not induce any teratogenic changes in the offspring of either mice or rats. The route of administration has been a determinant in the choice of a cephalosporin antibiotic. It is a distinct therapeutic advantage that a single cephalosporin antibiotic, cephradine, may be used in both oral and parenteral preparations[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 8.33 mg/mL (23.84 mM), Sonication is recommended. DMSO : 3.6 mg/mL (10.30 mM) |
| Keywords | Gram-negative | Cephradine | Grampositive | Antibiotic | Oral | TOPK | SQ11436 | Genitourinary | Gastrointestinal | Bacterial | Infections | Inhibitor | SQ 11436 | inhibit | Cefradine |
| Inhibitors Related | Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | EDTA copper(II) disodium salt | Dimethyl sulfoxide | Crystal Violet |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Pain-Related Compound Library | Approved Drug Library | Kinase Inhibitor Library | Drug Repurposing Compound Library | FDA-Approved Kinase Inhibitor Library | FDA-Approved Drug Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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