Ceefourin 1 NEW
Price | $36 | $51 | $80 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-14 |
Product Details
Product Name: Ceefourin 1 | CAS No.: 315702-40-0 |
Purity: 98.4% | Supply Ability: 10g |
Release date: 2024/11/14 |
Product Introduction
Bioactivity
名稱 | Ceefourin 1 |
描述 | Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor. |
體外活性 | Ceefourin 1 and Ceefourin 2, that inhibit transport of a broad range of MRP4 substrates, yet are highly selective for MRP4 over other ABC transporters, including P-glycoprotein (P-gp), ABCG2 (Breast Cancer Resistance Protein;?BCRP) and MRP1 (multidrug resistance protein 1;?ABCC1).?Both compounds are more potent MRP4 inhibitors in cellular assays than the most widely used inhibitor, MK-571, requiring lower concentrations to effect a comparable level of inhibition.?Furthermore, Ceefourin 1 and Ceefourin 2 have low cellular toxicity, and high microsomal and acid stability. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 11 mg/mL (37.36 mM) |
關鍵字 | P-glycoprotein | chemosensitizers | inhibit | efflux | protein | resistance | Ceefourin1 | MRP4 | HEK293 | D-luciferin | ABC | ABCG2 | P-gp | multidrug | MRP1 | Ceefourin 1 | Inhibitor | neuroblastoma | Ceefourin-1 | ABCC1 | BCRP |
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相關庫 | 經(jīng)典已知活性庫 | 膜蛋白靶向化合物庫 | 抑制劑庫 | NO PAINS 化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Address: 36?Washington?Street, Wellesley?Hills
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