CCR6 inhibitor 1 NEW
| Price | $118 | $297 | $446 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-16 |
Product Details
| Product Name: CCR6 inhibitor 1 | CAS No.: 2437547-04-9 |
| Purity: 98.91% | Supply Ability: 10g |
| Release date: 2024/11/16 |
Product Introduction
Bioactivity
| 名稱 | CCR6 inhibitor 1 |
| 描述 | CCR6 inhibitor 1 is an effective and selective inhibitor of CCR6 (IC50 of monkey and human CCR6 was 0.45 nM and 6 nM, respectively). CCR6 is associated with both autoimmune and non-autoimmune diseases, so CCR6 inhibitor 1 is useful for in vitro and in vivo pathophysiology studies as a small molecule inhibitor of CCR6. |
| 體外活性 | CCR6 inhibitor 1 in human CCR6-transfected CHO cells showed a good correlation between Gi signal inhibitory activity and cell migration inhibitory activity, which could effectively inhibit CCR6-dependent cell migration and ERK phosphorylation increase in human primary cells[1]. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 112.5 mg/mL (223.0 mM) |
| 關(guān)鍵字 | CCR-6 inhibitor 1 | CCR6 inhibitor 1 |
| 相關(guān)產(chǎn)品 | Aplaviroc | AZD2098 | MLN-3897 TFA | CCR2 antagonist 5 | INCB-9471 | CCR3 antagonist 1 | BMS-817399 | PF-4136309 | C-021 | Pirfenidone | Vercirnon | CCR6 antagonist 1 |
| 相關(guān)庫(kù) | 經(jīng)典已知活性庫(kù) | 細(xì)胞因子抑制劑庫(kù) | 膜蛋白靶向化合物庫(kù) | 抑制劑庫(kù) | 腫瘤免疫治療小分子化合物庫(kù) | 免疫/炎癥分子化合物庫(kù) | 已知活性化合物庫(kù) | 含氟化合物庫(kù) | GPCR靶點(diǎn)分子庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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