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Postion:Product Catalog >CCF0058981
CCF0058981
  • CCF0058981

CCF0058981 NEW

Price $38 $93 $163
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: CCF0058981 CAS No.: 2708934-53-4
Purity: 97.31% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameCCF0058981
DescriptionCCF0058981 (CCF981) is a 3-chlorophenyl analogue, serving as a noncovalent inhibitor of SARS-CoV-2 3CL pro (SC2), demonstrating potent activity with an IC50 of 68 nM. It also exhibits inhibitory effects against SARS-CoV-1 3CL pro (SC1) with an IC50 of 19 nM, highlighting its antiviral efficacy and potential in COVID-19 research [1].
In vitroCCF0058981 (CCF981) demonstrates inhibition of cytopathic effect (CPE) and plaque reduction in vitro viral replication, with EC50 values of 497 nM and 558 nM, respectively [1]. Additionally, its 50% cytotoxic concentration (CC50) in the CPE antiviral assay exceeds 50 μM [1]. The compound has a half-life (T1/2) of 21.1 minutes and a clearance rate (CLint) of 141 mL/min/kg in human liver microsomes [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 1 mg/mL (2.26 mM), Sonication is recommended.
KeywordsCCF 0058981 | CCF-0058981 | CCF0058981
Inhibitors RelatedNirmatrelvir | EIDD-1931 | Remdesivir | Andrographolide | Silymarin | Umifenovir hydrochloride | Hydroxychloroquine | Ritonavir | Chloroquine phosphate | Chloroquine | Favipiravir | Imatinib
Related Compound LibrariesBioactive Compound Library | Anti-Viral Compound Library | Inhibitor Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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