CB2R PAM NEW
Price | $51 | $122 | $179 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-16 |
Product Details
Product Name: CB2R PAM | CAS No.: 2244579-87-9 |
Purity: 98.17% | Supply Ability: 10g |
Release date: 2024/11/16 |
Product Introduction
Bioactivity
名稱 | CB2R PAM |
描述 | CB2R PAM is an orally active cannabinoid type 2 receptor (CB2Rs) positive allosteric modulator that enhances CP 55940 and 2-Arachidonylglycerol-stimulated [35S]GTPγS binding to CB2 receptors without affecting receptor activity in the absence of agonists. CB2R PAM shows anti-injury activity in a mouse model of neuropathic pain. |
體外活性 | CB2R Positive Allosteric Modulator (PAM) at a concentration of 100 nM notably enhances the capability of CP55940 and 2-AG, without affecting AEA, in promoting [35S]GTPγS binding to CB2 receptors.[1] |
體內(nèi)活性 | CB2R PAM (1-20 mg/kg; p.o.) exhibits antinociceptive activity. [1] |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 45.0 mg/mL (103.4 mM), Sonication is recommended. |
關(guān)鍵字 | CB2R PAM |
相關(guān)產(chǎn)品 | β-Caryophyllene | CB2 modulator 1 | Pregnenolone | CB1 inverse agonist 1 | Pregnenolone acetate | CB1 antagonist 2 | OMDM-5 | CB2 receptor agonist 2 | AM-1235 | 2,3-Butanediol | Drinabant | AM281 |
相關(guān)庫 | 經(jīng)典已知活性庫 | 疼痛相關(guān)化合物庫 | 膜蛋白靶向化合物庫 | 已知活性化合物庫 | GPCR靶點(diǎn)分子庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$2500.00/100mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-28 | |
$2580.00/50mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-10-28 | |
$19.00/10kg |
VIP1Y
|
Shandong Juchuang Chemical Co., LTD
|
2024-03-13 |
- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY