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Postion:Product Catalog >CB-103
CB-103
  • CB-103

CB-103 NEW

Price $33
Package 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: CB-103 CAS No.: 218457-67-1
Purity: 99.44% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameCB-103
DescriptionCB-103 is a orally active inhibitor of notch signaling pathway, with anti-tumor activity.
In vitroCB-103 has shown the ability to block NOTCH signaling in human T cell acute lymphoblastic leukemia cancer cell lines, and exhibits anti-tumor efficacy in GSI resistant T-ALL cell lines[2].
In vivoCB-103inhibits growth of GSI/Mab resistant triple negative breast cancer, andexhibits anti-tumor activity in xenograft models of human T-ALL and mouse mammary tumors[3].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (206.34 mM), Sonication is recommended.
KeywordsCB 103 | CB-103 | pathway | CB103 | inhibit | Inhibitor | Notch | signaling | leukemia
Inhibitors RelatedValproic acid sodium salt | Aβ42-IN-2 | Tangeretin | gamma-secretase modulator 1 | FLI-06 | Valproic Acid | Gossypolone | Carvacrol | RO7185876 | DAPT
Related Compound LibrariesAnti-Pancreatic Cancer Compound Library | Anti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Anti-Breast Cancer Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Recommended supplier

Product name Price   Suppliers Update time
$39.00/2mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-19
$1520.00/25mg
VIP1Y
TargetMol Chemicals Inc.
2024-10-28
$250.00/10gram
VIP3Y
Wuhan Senwayer Century Chemical Co.,Ltd
2022-10-31
$33.00/100mg
VIP3Y
TargetMol Chemicals Inc.
2024-11-19
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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