CAY10786 NEW

Price	$34	$55	$89
Package	2mg	5mg	10mg

Min. Order:
Supply Ability:	10g
Update Time:	2024-11-19

Product Details

Product Name: CAY10786	CAS No.: 1239987-91-7
Purity: 99.84%	Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

Name	CAY10786
Description	CAY10786 (GPR52 antagonist-1) is an antagonist of G protein-coupled receptor 52 (GPR52, IC50 = 0.63 μM).
In vitro	CAY10786 reduces mutant huntingtin (mHTT) protein levels in STHdhQ7/Q111cells in a concentration-dependent manner. CAY10786 (3 μM) reduces apoptosis induced by growth factor deprivation in primary striatal neurons[1].
In vivo	In the homozygous HdhQ140 mouse model of Huntington’s disease, CAY10786 (5 mg/kg) increases the latency to fall in the rotarod test and decreases striatal levels of soluble and insoluble mHTT[1].
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	Chloroform : 10 mg/mL DMSO : 245 mg/mL (1010.98 mM), Sonication is recommended.
Keywords	Inhibitor \| Huntington’s disease \| inhibit \| HdhQ140 \| CAY10786 \| CAY 10786 \| CAY-10786
Inhibitors Related	Vincamine \| Monomethyl fumarate \| Questiomycin A \| 3-Hydroxyoctanoic Acid \| CRTh2 antagonist 2 \| Fezagepras sodium \| Benzyl nicotinate \| 1-methoxycyclopropanecarboxylic acid \| TUG-1375 \| CAY10595 \| Timapiprant \| NF-56-EJ40
Related Compound Libraries	Bioactive Compound Library \| Membrane Protein-targeted Compound Library \| Inhibitor Library \| Bioactive Compounds Library Max \| GPCR Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.