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Postion:Product Catalog >CALP3 acetate(261969-05-5 free base)
CALP3 acetate(261969-05-5 free base)
  • CALP3 acetate(261969-05-5 free base)

CALP3 acetate(261969-05-5 free base) NEW

Price $137 $556 $783
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: CALP3 acetate(261969-05-5 free base) Purity: 96.49%
Supply Ability: 10g Release date: 2024/11/19

Product Introduction

Bioactivity

NameCALP3 acetate(261969-05-5 free base)
DescriptionCALP3 acetate is a potent Ca2+ channel blocker that activates EF hand motifs of Ca2+-binding proteins. CALP3 acetate can functionally mimic increased [Ca2+]i by modulating the activity of Calmodulin (CaM), Ca2+ channels and pumps.
In vitroCALP3 inhibits glutamate caused a large sustained increase in [Ca2+]i in a dose-dependent manner (IC50=37.25 μM) in Fura-2-loaded neuronal cultures. CALP3 inhibits glutamate-induced cytotoxicity in a dose-dependent manner (IC50=50.97 μM) in cultured rat neocortical neurons. CALP3 causes dose-dependent inhibition of apoptosis (IC50=33.41 μM). CALP3 (100 μM) inhibits apoptosis induced by HIV gp120 and SAg in Human T cells. CALP3 (100?μM; 15?min pretreatment) reduces gossypol-induced necrosis and increases the fraction of live cells[1][2].
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
KeywordsCALP-3 acetate(261969-05-5 free base) | CALP3 acetate(261969055 free base) | CALP3 acetate(261969 05 5 free base) | CALP3 acetate(261969-05-5 free base)
Inhibitors RelatedL-Ascorbic acid | Ethyl cinnamate | 1-Octanol
Related Compound LibrariesPain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Calcium Channel Compound Library | Peptide Compound Library | Neuroprotective Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

Recommended supplier

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2024-05-24
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Wuhan Quanjinci New Material Co.,Ltd.
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TargetMol Chemicals Inc.
2024-10-28
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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