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Postion:Product Catalog >API>Antibiotics>Calicheamicin
Calicheamicin
  • Calicheamicin

Calicheamicin NEW

Price $228 $572 $822
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Calicheamicin CAS No.: 108212-75-5
Purity: 98.78% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameCalicheamicin
DescriptionCalicheamicin (Calicheamicin γ1) is an antitumor antibiotic and is a DNA synthesis inhibitor. It also is a cytotoxic agent that causes double-strand DNA breaks.
In vitroPF-06647263 (anti-EFNA4-ADC) is generated by conjugating hE22 lysine residues to the AcButDMH-N-Ac-calicheamicin-γ1 linker-payload, with an average drug-to-antibody ratio (DAR) of 4.6. PF-06647263 induces antigen- and concentration-dependent cytotoxicity, causing cell death after 96 hours of exposure (EC50: ~1 ng/mL) [1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 100 mg/mL (73.08 mM)
KeywordsADC Cytotoxin | Calicheamicin r1 | Bacterial | Inhibitor | Apoptosis | Calicheamicin | inhibit | ADC Payload | Calicheamicin gamma1 | Calicheamicin γ 1 | DNA Alkylator/Crosslinker | Calicheamicin γ-1 | Antibiotic
Inhibitors RelatedMethotrexate | Dexamethasone acetate
Related Compound LibrariesAnti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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