Calcifediol NEW
| Price | $44 | $97 | $155 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-15 |
Product Details
| Product Name: Calcifediol | CAS No.: 19356-17-3 |
| Purity: 99.28% | Supply Ability: 10g |
| Release date: 2024/11/15 |
Product Introduction
Bioactivity
| 名稱 | Calcifediol |
| 描述 | Calcifediol (U 32070E) is a naturally occurring product that is metabolized in the liver from vitamin D3, a VDR ligand. Calcifediol is indicated for use as a vitamin supplement for all patients with vitamin D deficiency. |
| 體外活性 | Calcifediol, whether in liposomes or ethanolic solution, does not affect the release of the proinflammatory cytokine KC from Pseudomonas-infected murine epithelial cells. However, treating infected human bronchial 16-HBE cells with Calcifediol liposomes significantly reduces bacterial survival [1]. |
| 體內(nèi)活性 | METHODS: Calcifediol (25 μg/kg) was administered dietary to rats for four weeks to study its role in pregnancy. RESULTS: Calcifediol provided better vitamin D availability to the mother and fetus when administered during pregnancy compared to vitamin D3. No adverse effects on pregnancy outcome were observed, and further studies are needed to investigate the effects of Calcifediol on fetal brain VDR and GAD67 expression. [3] |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 18.33 mg/mL (45.76 mM) Ethanol : 16 mg/mL (39.9 mM) H2O : < 1 mg/mL (insoluble or slightly soluble) |
| 關(guān)鍵字 | Calcifediol | Vitamin D receptor | VD/VDR | Vitamin D | Inhibitor | inhibit | Endogenous Metabolite |
| 相關(guān)產(chǎn)品 | Sucrose | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | Vanillin | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid | Oleic acid |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 天然產(chǎn)物庫 | 抑制劑庫 | FDA 上市藥物庫 | 高通量篩選天然產(chǎn)物庫 | 人內(nèi)源代謝化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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