BzATP triethylammonium salt NEW
| Price | $41 | $97 | $155 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: BzATP triethylammonium salt | CAS No.: 112898-15-4 |
| Purity: 96.26% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | BzATP triethylammonium salt |
| Description | BzATP triethylammonium salt is a P2X7 receptor agonist. |
| In vitro | METHODS: Glioma cell lines U87 and U251 were treated with BzATP triethylammonium salt (5-1000 μM) for 2-72 h. Cell proliferation was detected by MTT assay. RESULTS: Proliferation of glioma cell lines U87 and U251 was significantly increased in the presence of BzATP. the peak fine cell proliferation of both U87 and U251 cell lines was 100 μM BzATP, and the optimal incubation time was 24 h for both cell lines [1]. METHODS: Retinal ganglion cells were treated with BzATP triethylammonium salt (50 μM) for 2 min and intracellular Ca2+ levels were measured. RESULTS: The P2X7 agonist BzATP resulted in a rapid increase in intracellular Ca2+ and the level remained elevated for 2 min after agonist application. More than 80% of the examined cells responded strongly to BzATP. [2] |
| In vivo | METHODS: To investigate the effects on whole-body energy metabolism, BzATP triethylammonium salt (1 mg/kg) was administered intraperitoneally to C57BL/6J mice once daily for seven days. RESULTS: BzATP triethylammonium salt increased metabolic rate and O2 consumption while decreasing respiratory rate and upregulating NADPH oxidase 2 in gastrocnemius and tibialis anterior muscle.The findings suggest that activation of P2X7 has a significant effect on energy homeostasis and muscle metabolism. [3] |
| Storage | store at low temperature,keep away from moisture,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 50 mg/mL (49.06 mM), Sonification is recommended. DMSO : 50 mg/mL (49.06 mM), Sonification is recommended. |
| Keywords | BzATP triethylammonium | BzATP triethylammonium salt |
| Inhibitors Related | Aurintricarboxylic acid | (E/Z)-Sivopixant | PSB-12062 | ATP disodium salt | Oxatomide | JNJ-42253432 | Ivermectin | Lappaconitine | CTP disodium dihydrate | Brilliant blue G-250 |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Peptide Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Nucleotide Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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