Product Details
Product Name:
Bromosporine |
CAS No.:
1619994-69-2 |
Purity:
99.65% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | Bromosporine |
Description | Bromosporine is a broad spectrum inhibitor for bromodomains for BRD2/4/9 and CECR2 (IC50: 0.41/0.29/0.122/0.017 μM), respectively. |
In vitro | Bromosporine (1 μM) accelerates FRAP recovery of BRD4 and CREBBP, while shows no activities against TIF1α, BAZ2A, and SMARCA2 even at 10 μM. Bromosporine (18 μM) has moderate cytotoxicity in HeLa cells. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 55 mg/mL (135.99 mM)
|
Keywords | KASUMI-1 | HIV | AIDS | Human immunodeficiency virus | MV4;11 | inhibit | AML | colorectal cancer | CDK | antitumor | T cells | HCT116 | Apoptosis | Bromosporine | HT29 | anticancer | Epigenetic Reader Domain | Inhibitor | Cyclin dependent kinase |
Inhibitors Related | Ribociclib | 3-methyl-1,2,3,4-tetrahydroquinazolin-2-one | (+)-JQ-1 | Curcumin | Palbociclib monohydrochloride | CASIN | Palbociclib | Naphthol AS-E | Sodium Oxamate | Abemaciclib | Dinaciclib | Abemaciclib methanesulfonate |
Related Compound Libraries | Reprogramming Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Chromatin Modification Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Cell Cycle Compound Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$1.00/1KG |
VIP7Y
|
Career Henan Chemical Co
|
2018-08-20 |