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Postion:Product Catalog >API>Nervous system drugs>Antiparkinson Drugs>Bromocriptine mesylate
Bromocriptine mesylate
  • Bromocriptine mesylate

Bromocriptine mesylate NEW

Price $59
Package 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Bromocriptine mesylate CAS No.: 22260-51-1
Purity: 99.87% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameBromocriptine mesylate
DescriptionBromocriptine mesylate (CB-154) is a potent dopamine receptor agonist that binds the D2 receptor with highest affinity (Ki = 2.5 nM)
In vitroThe ergot alkaloid bromocriptine (BKT) was found to act as a strong inhibitor of purified neuronal nitric oxide synthase (NOS) (IC50 = 10 +/- 2 microM) whereas it was poorly active towards inducible macrophage NOS (IC50 > 100 microM). BKT affects the activation of NOS by calmodulin, as it not only inhibits L-arginine oxidation to NO and L-citrulline but also NADPH oxidation and calmodulin-dependent cytochrome c reduction catalyzed by neuronal NOS. These results suggest that BKT could exert some of its therapeutic effects by interfering with the NOS-dependent formation of nitric oxide and/or superoxide ion in various tissues.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (66.6 mM), Sonication is recommended.
KeywordsDopamine Receptor | Autophagy | Bromocriptine Mesylate | Bromocriptine | CB 154 | Inhibitor | inhibit | Bromocriptine mesylate | CB154
Inhibitors RelatedStavudine | Sodium 4-phenylbutyrate | Hydroxychloroquine | Guanidine hydrochloride | Taurine | Curcumin | Oxyresveratrol | Paeonol | Naringin | Gefitinib
Related Compound LibrariesAnti-Neurodegenerative Disease Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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