Product Details
| Product Name:
BPH-1086 |
CAS No.:
1226901-43-4 |
| Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
| Name | BPH-1086 |
| Description | BPH-1086 (compound 10) is an inhibitor of IspH, a domain that, when fused with ribosomal protein S1 (RPS1), can bind to mRNA or form part of the bacterial ribosome [1] [2]. |
| In vitro | IspH, also known as LytB, serves as the terminal enzyme in the nonmevalonate pathway. It possesses domains that may merge with the ribosomal protein S1 (RPS1), enabling IspH-RPS1 to either attach to mRNA or become integrated into the bacterial ribosome. This configuration is prevalent in anaerobic bacteria residing in the human gut, including pathogenic strains such as Clostridium botulinum, C. tetani, and Fusobacterium nucleatum. Consequently, inhibiting IspH not only directly eradicates bacteria, similar to conventional antibiotics but also targets persistent bacterial populations through microptosis. |
| Storage | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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