BMS-986165
Price | Get Latest Price | ||
Package | 1kg | 10kg | 1000kg |
Min. Order: | 25kg |
Supply Ability: | 20tons |
Update Time: | 2023-07-25 |
Product Details
Product Name: BMS-986165 | CAS No.: 1609392-27-9 |
Min. Order: 25kg | Purity: 99.5% |
Supply Ability: 20tons | Release date: 2023/07/25 |
Chinese name: BMS-986165
Chinese synonym: compound BMS-986165; BMS-986165; BMS986165; BMS986165; DEUCRAVACITINIB
English name: BMS-986,165
English synonym: BMS-986165; Tyk2-IN-4; TYK2-IN-4; BMS986165; BMS-986165; BMS986165; 6-(cyclopropanecarboxamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide; Deucravacitinib; Deucravacitinib(BMS986165); Deucravacitinib(TYK2-IN-4;6-cyclopropaneamido-4-{[2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl]amino}-N-(2H?)methylpyridazine-3-carboxamide
CAS No.: 1609392-27-9
Molecular formula: C20H22N8O3
Molecular weight: 422.45EINECS No.:
Related categories: new products; Inhibitors; Pharmaceutical and chemical raw materials; Fine chemical products; Standards; Pharmaceutical raw materials; Belka; API; APIS; APIMol file: 1609392-27-9.molBMS-986165 Property: BMS-986165
Application and synthesis method
Purposes BMS-986,165 is a new type of oral selective TYK2 inhibitor. Its unique mechanism of action is expected to provide a promising oral choice to help patients effectively control their psoriasis.
The bioactive Deucravacitinib (BMS-986165) is a powerful and selective allosteric inhibitor of Tyk2. The Ki value of its binding to the pseudo kinase domain of Tyk2 is 0.02 nM. It is highly selective for a group of 265 kinases and pseudokinases. TargetValueTyk2 (Cell freeassay) 0.02nM
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