Bisacodyl NEW
| Price | $42 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Bisacodyl | CAS No.: 603-50-9 |
| Purity: 99.78% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Bisacodyl |
| Description | Bisacodyl (Fenilaxan) is a diphenylmethane stimulant laxative used for the treatment of constipation and for bowel evacuation. |
| In vitro | Bisacodyl inhibits the absorption of water in rats' jejunum, ileum, and colon, with the degree of inhibition linearly correlated to the logarithm of bisacodyl concentration. At a dosage of 4.3 mg/kg, bisacodyl, in combination with AOM, increases the number of microcysts per colony in rats without increasing tumor numbers. However, a higher dosage of 43 mg/kg significantly raises both the microcyst and tumor counts. Compared to rats treated with saline, bisacodyl (5.9 mg/kg) significantly reduces the activity of jejunum and colon (Na + K) ATPases. Furthermore, at 5.9 mg/kg, bisacodyl markedly increases PGE2 levels and stimulates adenylate cyclase activity in the jejunum and colon, without affecting cAMP levels. Oral administration of 10 mg/kg bisacodyl significantly decreases NOS activity in the rat jejunum. Meanwhile, 20 mg/kg bisacodyl leads to a reduction in AQP3 protein expression and an increase in TNF-α mRNA expression levels in the rat colon. |
| In vivo | At a concentration of 10 μg/mL, Bisacodyl acts on Raw264.7 cells, leading to an increase in the mRNA expression levels of TNF-α, COX2, and PGE2. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 55 mg/mL (152.19 mM), Sonication is recommended. Ethanol : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | Inhibitor | Opioid Receptor | Dopamine Transporter | DAT | Bisacodyl | inhibit | SLC6A3 |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Drug-induced Liver Injury (DILI) Compound Library | Drug Repurposing Compound Library | NO PAINS Compound Library | FDA-Approved Drug Library | Orally Active Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $150.00/1kg |
VIP1Y
|
Hebei Zhuanglai Chemical Trading Co Ltd
|
2024-11-25 | |
| $1.00/1kg |
VIP2Y
|
Jinan Million Pharmaceutical Co., Ltd
|
2024-07-24 | |
| $30.00/1kg |
VIP1Y
|
hebei hongtan Biotechnology Co., Ltd
|
2024-03-22 | |
| $0.00/25KG |
VIP5Y
|
Hebei Mojin Biotechnology Co., Ltd
|
2024-01-16 | |
| $0.00/1kg |
VIP3Y
|
Nanjing Kaitian Chemical Co., LTD
|
2023-02-10 | |
| $0.00/25kg |
PNP Biotech Co. Ltd
|
2022-09-16 | ||
| $0.00/1g |
Wuhan Godbullraw Chemical Co.,ltd
|
2022-05-17 | ||
| $0.00/1KG |
Wuhan Godbullraw Chemical Co.,ltd
|
2022-05-10 | ||
| $1.00/1KG |
VIP4Y
|
WUHAN FORTUNA CHEMICAL CO., LTD
|
2021-12-27 | |
| $15.00/1KG |
Zhuozhou Wenxi import and Export Co., Ltd
|
2021-07-10 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY