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Postion:Product Catalog >API>Synthetic Anti-infective Drugs>Quinolones>Besifloxacin Hydrochloride
Besifloxacin Hydrochloride
  • Besifloxacin Hydrochloride

Besifloxacin Hydrochloride NEW

Price $32 $52 $98
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Besifloxacin Hydrochloride CAS No.: 405165-61-9
Purity: 99.95% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameBesifloxacin Hydrochloride
DescriptionBesifloxacin Hydrochloride (BOL-303224-A) is a fourth-generation fluoroquinolone antibiotic.
Kinase Assay20 ng of purified human DDK, together with increasing concentrations of each DDK inhibitor is pre-incubated for 5 min. Then 10 μCi (γ)-32P ATP and 1.5 μM cold ATP are added in a buffer containing 50 mM Tris-HCl (pH 7.5), 10 mM MgCl2, and 1 mM DTT and incubated for 30 min at 30°C. The proteins are denatured in 1X Laemmli buffer at 100°C followed by SDS-PAGE and autoradiography on HyBlot CL film. DDK kinase activity is indicated by Auto-phosphorylation of DDK. 32P-labeled bands are quantified using ImageJ and the IC50 values are calculated using GraphPad.
In vitroBesifloxacin has effectively bactericidal activity against prevalent and drug-resistant pathogens. Besifloxacin is the most potent agent tested against gram-positive pathogens and anaerobes and is generally equivalent to comparator fluoroquinolones in activity against most gram-negative pathogens. Besifloxacin demonstrates potent, broad-spectrum activity, which is particularly notable against gram-positive and gram-negative isolates that are resistant to other fluoroquinolones and classes of antibacterial agents.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 11 mg/mL (25.56 mM)
KeywordsBesivance Hydrochloride | Antibiotic | Besifloxacin | Bacterial | Besifloxacin Hydrochloride | Inhibitor | inhibit
Inhibitors RelatedNeomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | EDTA copper(II) disodium salt | Dimethyl sulfoxide | Crystal Violet
Related Compound LibrariesBioactive Compound Library | Antibiotics Library | Drug Repurposing Compound Library | Anti-Viral Compound Library | FDA-Approved Drug Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
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