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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Belzutifan
Belzutifan
  • Belzutifan

Belzutifan NEW

Price $64 $155 $289
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Belzutifan CAS No.: 1672668-24-4
Purity: 99.41% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameBelzutifan
DescriptionBelzutifan (MK-6482) is a potential treatment for clear cell renal cell carcinoma (ccRCC). Belzutifan is an orally active and selective HIF-2α inhibitor (IC50: 9 nM). Belzutifan , as a second-generation HIF-2α inhibitor, increases potency and improves pharmacokinetic profile.
In vitroPT2977 effectively and dose-dependently decreased mRNA levels of human cyclin D1, a target gene regulated by HIF-2α. It leads to a rapid and dose-dependent reduction in EPO expression[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 65 mg/mL (169.56 mM), Sonication is recommended.
KeywordsInhibitor | PT 2977 | HIFs | MK 6482 | HIF/HIF Prolyl-Hydroxylase | inhibit | HIF-PH | Belzutifan | Hypoxia-inducible factors | PT-2977 | MK6482
Inhibitors RelatedM1002 | Dapagliflozin | ZINC13466751 | DMOG | PT-2385 | Roxadustat | Hydroxycitric acid tripotassium hydrate | Pantoprazole sodium | Oltipraz | Vadadustat | Acriflavine Hydrochloride | Cinnamaldehyde
Related Compound LibrariesBioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Angiogenesis related Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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