BAY-899 NEW
Price | $1167 | $2568 | $3852 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-18 |
Product Details
Product Name: BAY-899 | CAS No.: 2471967-92-5 |
Supply Ability: 10g | Release date: 2024/11/18 |
Product Introduction
Bioactivity
Name | BAY-899 |
Description | BAY-899 is an orally active and selective antagonist of the luteinizing hormone receptor (LH-R), with IC50 values of 185 nM for human LH (hLH) and 46 nM for rat LH (rLH). In vivo studies have shown that BAY-899 effectively reduces sex hormone levels[1]. |
In vivo | BAY-899, administered orally at a dosage of 12.5 mg/kg/day for 8 days, effectively reduces serum estradiol levels in intact female rats. In both female and male Wistar rats, BAY-899 demonstrates a half-life (t 1/2) of 11 hours when given intravenously (iv) at 0.5 mg/kg and 12 hours when administered orally (po) at 2 mg/kg. Additionally, the maximum concentration (Cmax) achieved is 0.97 kg/L for the intravenous route and 0.24 kg/L for the oral route. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Keywords | BAY-899 | BAY899 | BAY 899 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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