BAM 15 NEW
| Price | $59 | $109 | $197 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: BAM 15 | CAS No.: 210302-17-3 |
| Purity: 99.89% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | BAM 15 |
| Description | BAM 15 is an uncoupler of mitochondrial protonophore. |
| In vitro | BAM 15 effectively enhances mitochondrial respiration and oxygen consumption across a wide concentration range without increasing reactive oxygen species (ROS), displaying a broader range of action compared to FCCP in myoblasts and hepatocytes. Despite structural differences from FCCP, BAM 15 at concentrations between 100 nM and 1 μM increases the cellular oxygen consumption rate (OCR) similarly to FCCP, but at higher concentrations (1 μM to 50 μM), it sustains uncoupled respiration more effectively across various cell lines. Additionally, BAM 15 causes mitochondrial swelling, indicating its role as a protonophore, and demonstrates greater cell viability than FCCP when used up to 50 μM[1]. |
| In vivo | Animals that receive BAM 15 are protected from kidney injury compared to vehicle-treated mice, such as indicated by lower plasma creatinine levels at 24 and 48 h post-ischemia, reduced tubular necrosis, less obstruction of proximal tubules, less depletion of brush border villi, and less immune cell infiltration[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 16.67 mg/mL (48.98 mM), Sonication is recommended. |
| Keywords | inhibit | BAM15 | BAM-15 | BAM 15 | Inhibitor | Mitochondrial Metabolism |
| Inhibitors Related | Imeglimin hydrochloride | Rotenone | Glibenclamide | Tricarballylic acid | Thiabendazole | Boscalid | α-Lipoic Acid | (-)-Epigallocatechin Gallate | Lipoic acid | Daidzin | D-Histidine | Nerol |
| Related Compound Libraries | Cuproptosis Compound Library | Apoptosis Compound Library | Bioactive Compound Library | Mitochondria-Targeted Compound Library | NO PAINS Compound Library | Metabolism Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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