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Postion:Product Catalog >BAL-0028
BAL-0028
  • BAL-0028

BAL-0028 NEW

Price $195 $483 $692
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: BAL-0028 CAS No.: 2842012-69-3
Purity: 99.16% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameBAL-0028
DescriptionBAL-0028 is a potent inhibitor of NLRP3 activation (IC50: 25 nM) with anti-inflammatory activity for cancer research.
In vitroA series of novel high-affinity, reversible inhibitors of NLRP3 activation were discovered by screening a DNA-encoded library, and a potent lead compound, BAL-0028, was identified directly from the screen with an IC50 value of 25 nM; SPR studies showed that BAL-0028 binds tightly to the NACHT domain of NLRP3 (KD range of 104-123 nM); CADD analysis of the interaction of BAL-0028 with the NLRP3 NACHT domain showed that the binding site is distinct from that of ADP and MCC950 and includes site-specific interactions. [1]
Storagekeep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Inhibitors RelatedDapansutrile | NOD-IN-1 | MCC950 sodium | Imperatorin | NLRP3-IN-10 | NLRP3-IN-2 | Bergenin | INF39 | NLRP3-IN-9 | Selnoflast

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.
2024-10-28
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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