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Postion:Product Catalog >B355252
B355252
  • B355252

B355252 NEW

Price $32
Package 1mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-12

Product Details

Product Name: B355252 CAS No.: 1261576-81-1
Purity: 99.92% Supply Ability: 10g
Release date: 2024/11/12

Product Introduction

Bioactivity

名稱B355252
描述B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.
體外活性Method: HT22 cells were pretreated for 2 hours with various concentrations of B355252 (0.625-20 μM). This was followed by the addition of 300 μM CoCl2 and incubation at 37oC for 24 hours. At the end of this time, cell viability was determined by resazurin assay as described below. Result: From 0.625 to 5 μM, B355252 increased cell viability in a dose-dependent manner, protecting against CoCl2-induced hypoxia. Above 5 μM, B355252 became toxic to the cells and, synergistically with CoCl2, decreased cell viability.
存儲條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 25 mg/mL (48.63 mM)
關(guān)鍵字neurite outgrowth | ischemic neurons | HT22 | glutamate | Inhibitor | Apoptosis | DNA damage | inhibit | NGF | LDH level | ROS production | B 355252 | Parkinson disease | phenoxy thiophene sulfonamide | B-355252 | B355252
相關(guān)庫經(jīng)典已知活性庫 | 神經(jīng)保護化合物庫 | NO PAINS 化合物庫 | 已知活性化合物庫

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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