Product Details
| Product Name:
Azumolene |
CAS No.:
64748-79-4 |
| Purity:
98.35% |
Supply Ability:
10g |
| Release date:
2024/11/19 |
Product Introduction
Bioactivity
| Name | Azumolene |
| Description | Azumolene (EU4093 free base) |
| In vivo | Azumolene is a direct acting, skeletal muscle relaxant with structural similarities to dantrolene sodium in that the para-nitro phenyl group of dantrolene sodium is replaced by a para-bromo phenyl group.2.The effect of Azumolene on the twitch of the intact rat soleus preparation is nearly maximal at a dose of 20 mg kg-1.This dose of Azumolene reduces the amplitude of the twitch to 31.9% of the control value.By comparison, dantrolene sodium reduced the twitch amplitude to 31.3% of the control value at a dose of 5 mg kg-1.3.The contraction of intrafusal muscle as measured by the response of spindle afferent discharge was also reduced by Azumolene.4.The most significant difference between the effect of Azumolene and dantrolene sodium on the contraction of intrafusal muscle was that Azumolene had an appreciable depressant action at high stimulation frequencies at which dantrolene sodium had only a minimal relaxant effect on the intrafusal muscle contraction. |
| Storage | keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 45 mg/mL (128.89 mM), Sonication is recommended.
|
| Keywords | SOCE | inhibit | ryanodine | EU-4093 | Inhibitor | Ca channels | EU 4093 | Calcium Channel | relaxant | Ca2+ channels | muscle | Azumolene | receptor | calcium | EU4093 |
| Inhibitors Related | L-Ascorbic acid | Ethyl cinnamate | 1-Octanol |
| Related Compound Libraries | Bioactive Compound Library | Pain-Related Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Neuroprotective Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:89-24-7
$29.00 / 50mg
-
CAS:2010159-45-0
$33.00 / 1mg
-
CAS:360-70-3
$38.00 / 25mg
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$1980.00/50mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-28 |
United States