Product Details
Product Name:
AZD5904 |
CAS No.:
618913-30-7 |
Purity:
99.70% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | AZD5904 |
Description | AZD5904 is a potent and irreversible inhibitor of human Myeloperoxidase (MPO, IC50: 140 nM) which has similar potency in mouse and rat. |
In vitro | In isolated human neutrophils, 1 μM AZD5904 inhibits PMA stimulated HOCl by >90%[1]. It is 10 to 19-fold selective compare to the closely related lactoperoxidase and thyroid peroxidase. For a broad panel of other enzymes, ion channels, and receptors, is higher than >70-fold. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 65 mg/mL (257.64 mM), Sonication is recommended.
|
Keywords | AZD 5904 | Inhibitor | Glutathione Peroxidase | inhibit | AZD5904 | AZD-5904 |
Inhibitors Related | AZD8309 | ML-210 | RSL3 | ML162 | PF-1355 | 5-Aminosalicylic Acid | Melatonin | 4-POBN | 4-Methylesculetin | Nabumetone | Cefdinir | GSTO1-IN-1 |
Related Compound Libraries | Bioactive Compound Library | ReFRAME Related Library | Glutamine Metabolism Compound Library | Antioxidant Compound Library | Inhibitor Library | Metabolism Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Preclinical Compound Library | Oxidation-Reduction Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$48.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 |