AZD 3147 NEW
| Price | $98 | $222 | $355 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: AZD 3147 | CAS No.: 1101810-02-9 |
| Purity: 98.34% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | AZD 3147 |
| Description | AZD 3147 is an inhibitor of mTORC with IC50s of 40.7 and 5.75 nM for mTORC1 and mTORC2. AZD 3147 shows IC50s of 912, 5495, 9333, and 6310 nM for PI3Kα, PI3Kβ, PI3Kδ, and PI3Kγ, respectively. |
| In vitro | In NIH3T3 cells, AZD3147 (1.5-50 nM) alleviates FGF-mediated cilia extension[2]. AZD3147 inhibits cell viability of neuroblastoma cell lines Kelly(IC50 = 0.88 nM) and IMR-32 (IC50 = 662.4 nM)[3]. |
| In vivo | AZD3147 shows a CL of 78 mL/min/kg, a Vss of 2.3 L/kg, a t1/2 of 0.9 h and an F of 61% in mice[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ethanol : 1 mg/mL Hydrochloride acid : 100 nM DMSO : 46.8 mg/mL (90.5 mM) |
| Keywords | AZD3147 | AZD 3147 | AZD-3147 |
| Inhibitors Related | α-Hydroxyglutaric Acid Lithium | L-Leucine | Capivasertib | Sapanisertib | Everolimus | Bimiralisib | Salidroside | Tacrolimus | GDC0084 | TMBIM6 antagonist-1 | Dihydromyricetin | Rapamycin |
| Related Compound Libraries | Bioactive Compound Library | Kinase Inhibitor Library | Anti-Obesity Compound Library | Anti-Cancer Metabolism Compound Library | Antioxidant Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Neuronal Differentiation Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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