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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Immunosuppressants>Azathioprine
Azathioprine
  • Azathioprine

Azathioprine NEW

Price $45
Package 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Azathioprine CAS No.: 446-86-6
Purity: 99.49% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameAzathioprine
DescriptionAzathioprine (BW 57-322), an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation.
In vitroIn murine and rat brain allografts, the combination of Azathioprine with Cyclosporin A or Prednisolone significantly enhances survival rates.
In vivoAzathioprine inhibits Rac1 target genes in primary human CD4+ T lymphocytes, leading to apoptosis via the mitochondrial pathway. In isolated rat hepatocytes, Azathioprine depletes reduced glutathione (GSH), releases lactate dehydrogenase, and decreases cellular viability.
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (180.34 mM), Sonication is recommended.
KeywordsRheumatic diseases | Infectious skin diseases | Apoptosis | inhibit | Autoimmunity inhibitor | Inhibitor | Azathioprine | 6-Mercaptopurine
Inhibitors RelatedStavudine | Sodium 4-phenylbutyrate | Tributyrin
Related Compound LibrariesAnti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Viral Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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