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Postion:Product Catalog >AZ7550 trimesylate salt
AZ7550 trimesylate salt
  • AZ7550 trimesylate salt

AZ7550 trimesylate salt NEW

Price $149
Package 1mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: AZ7550 trimesylate salt CAS No.: 2319837-99-3
Purity: 99.24% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameAZ7550 trimesylate salt
DescriptionAZ7550 trimesylate salt (AZ7550 Mesylate) is the active metabolite of ositinib, AZ7550 trimesylate salt inhibits IGF1R activity and can be used in the study of non-small cell lung cancer.
In vitroAZ7550 trimesylate salt (Compound 28) demonstrates a potency and selectivity profile broadly similar to the parent compound AZD9291. Inhibiting the double mutant (DM) cell line H1975, activating mutant (AM) cell line PC9, and wild-type (WT) cell line LoVo, AZ7550 trimesylate salt exhibits IC50s of 45, 26, and 786 nM, respectively. Moreover, it inhibits the antiproliferative cell lines H1975 (DM), PC9 (AM), and Calu3 (WT) with GI50s of 19, 15, and 537 nM, respectively[1].
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 20 mg/mL (25.84 mM), Sonication is recommended.
KeywordsAZ-7550 Mesylate (1421373-99-0 free base) | 1421373-99-0 free base | AZ 7550 Trimesylate | AZ7550 Mesylate (1421373990 free base) | AZ-7550 Mesylate | AZ7550 | AZ7550 Trimesylate | AZ 7550 | AZ-7550 Trimesylate | 1421373-99-0 | AZ-7550 | AZ7550 Mesylate (1421373 99 0 free base) | AZ 7550 Mesylate
Inhibitors RelatedInsulin (human) | I-OMe-Tyrphostin AG 538 | LY-364947 | Necrosulfonamide | Ceritinib | Brigatinib | GSK1904529A | HNMPA | PD173074 | Tyrphostin AG 538 | ALK-IN-1 | Linsitinib

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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