AZ7550 trimesylate salt NEW
Price | $149 |
Package | 1mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: AZ7550 trimesylate salt | CAS No.: 2319837-99-3 |
Purity: 99.24% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | AZ7550 trimesylate salt |
Description | AZ7550 trimesylate salt (AZ7550 Mesylate) is the active metabolite of ositinib, AZ7550 trimesylate salt inhibits IGF1R activity and can be used in the study of non-small cell lung cancer. |
In vitro | AZ7550 trimesylate salt (Compound 28) demonstrates a potency and selectivity profile broadly similar to the parent compound AZD9291. Inhibiting the double mutant (DM) cell line H1975, activating mutant (AM) cell line PC9, and wild-type (WT) cell line LoVo, AZ7550 trimesylate salt exhibits IC50s of 45, 26, and 786 nM, respectively. Moreover, it inhibits the antiproliferative cell lines H1975 (DM), PC9 (AM), and Calu3 (WT) with GI50s of 19, 15, and 537 nM, respectively[1]. |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 20 mg/mL (25.84 mM), Sonication is recommended. |
Keywords | AZ-7550 Mesylate (1421373-99-0 free base) | 1421373-99-0 free base | AZ 7550 Trimesylate | AZ7550 Mesylate (1421373990 free base) | AZ-7550 Mesylate | AZ7550 | AZ7550 Trimesylate | AZ 7550 | AZ-7550 Trimesylate | 1421373-99-0 | AZ-7550 | AZ7550 Mesylate (1421373 99 0 free base) | AZ 7550 Mesylate |
Inhibitors Related | Insulin (human) | I-OMe-Tyrphostin AG 538 | LY-364947 | Necrosulfonamide | Ceritinib | Brigatinib | GSK1904529A | HNMPA | PD173074 | Tyrphostin AG 538 | ALK-IN-1 | Linsitinib |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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