Autocamtide-2-Related Inhibitory Peptide trifluoroacetate salt
| Price | $10 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | Ex 20 tons |
| Update Time: | 2022-10-25 |
Product Details
| Product Name: Autocamtide-2-Related Inhibitory Peptide trifluoroacetate salt | CAS No.: 167114-91-2 |
| Min. Order: 1KG | Purity: 99% |
| Supply Ability: Ex 20 tons | Release date: 2022/10/25 |
| Name | Autocamtide 2-related inhibitory peptide |
|---|---|
| Synonym | More Synonyms |
| Description | Autocamtide-2-related inhibitory peptide is a highly specific and potent inhibitor of CaMKII with an IC50 of 40 nM. |
|---|---|
| Related Catalog | Signaling Pathways >> Neuronal Signaling >> CaMK Signaling Pathways >> Autophagy >> Autophagy Research Areas >> Neurological Disease |
| Target | IC50: 40 nM (CaMKII)[1]. |
| In Vitro | It is found that Autocamtide-2-related inhibitory peptide (a novel synthetic peptide ATP) is a potent inhibitor of CaM-kinase II with an IC50 of 40 nM, which is active in the presence or absence of Ca2+/calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93,respectively, under the assay condition used[1]. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Shipping | Room temperature |
| References | [1]. Ishida A, et al. A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochem Biophys Res Commun. 1995 Jul 26;212(3):806-12. |
| Molecular Formula | C64H116N22O19 |
|---|---|
| Molecular Weight | 1822.12000 |
| Exact Mass | 1821.07000 |
| PSA | 746.43000 |
| LogP | 8.46970 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Hazard Codes | Xn: Harmful; |
| Risk Phrases | 20/21/22-36 |
| Safety Phrases | 22-24/25-26 |
| RIDADR | NONH for all modes of transport |
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China- Since: 2022-02-24
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