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Postion:Product Catalog >Biochemical Engineering>Polypeptide>Atosiban
Atosiban
  • Atosiban

Atosiban NEW

Price $62 $92 $216
Package 5mg 10mg 50mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Atosiban CAS No.: 90779-69-4
Supply Ability: 10g Release date: 2024/11/19

Product Introduction

Bioactivity

NameAtosiban
DescriptionAtosiban (RW22164) is an inhibitor of the hormones oxytocin and vasopressin. It is used as an intravenous medication as a labour repressant (tocolytic) to halt premature labor. Atosiban inhibits the oxytocin-mediated release of inositol trisphosphate from the myometrial cell membrane. As a result, there is reduced release of intracellular, stored calcium from the sarcoplasmic reticulum of myometrial cells, and reduced influx of Ca2+ from the extracellular space through voltage gated channels. In addition, atosiban suppresses oxytocin-mediated release of PGE and PGF from the decidua. In human pre-term labor, atosiban, at the recommended dosage, antagonizes uterine contractions and induces uterine quiescence. The onset of uterus relaxation following atosiban is rapid, uterine contractions being significantly reduced within 10 minutes to achieve stable uterine quiescence.
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationH2O : 16.67 mg/mL (16.77 mM), Sonication is recommended.
DMSO : 16.67 mg/mL (16.77 mM)
Keywordsnonapeptide | Vasopressin Receptor | desamino-oxytocin | OXTR | vasopressin | tocolytic | RWJ 22164 | Ca2+ | Preterm | Inhibitor | maternal-fetal | inhibit | RW-22164 | RWJ-22164 | oxytocin | Oxytocin Receptor | RW 22164 | Atosiban
Inhibitors RelatedLIT-001 | Atosiban acetate | SSR126768A | Desmopressin acetate (16679-58-6 free base) | OPC-51803 | Felypressin acetate | Nelivaptan | Fuscoside | Tolvaptan

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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