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Postion:Product Catalog >API>Antiparasitic drugs>Antimalarial drugs>Artemisinin
Artemisinin
  • Artemisinin
  • Artemisinin
  • Artemisinin
  • Artemisinin
  • Artemisinin

Artemisinin NEW

Price Get Latest Price
Package 20kg 40kg 130kg
Min. Order: 20kg
Supply Ability: 200000
Update Time: 2024-12-06

Product Details

Product Name: Artemisinin CAS No.: 63968-64-9
EC-No.: 1806241-263-5 Min. Order: 20kg
Purity: 99% Supply Ability: 200000
Release date: 2024/12/06

99% Artemisinin CAS:63968-64-9 Use for anticancer

 

 

Product Name:Artemisinin

Synonyms:3,12-epoxy-12h-pyranol(4,3-j)-1,2-benzodioxepin-10(3h)-one,octahydro-3,6,9-tri;artemisiaannual.,extract;huanghuahaosu;octahydro-3,6,9-trimethyl-3,12-epoxy-12h-pyrano(4,3-j)-1,2-benzodioxepin-10(;qinghausau;qinghausu;QHS;ARTEMISININ 99%

CAS:63968-64-9

MF:C15H22O5

MW:282.33

EINECS:  1806241-263-5

Melting point:156-157 °C (lit.)

alpha:76 o (c=0.5,MeOH)

Boiling point:344.94°C (rough estimate)

density:1.0984 (rough estimate)

refractive index:75 ° (C=0.5, MeOH)

storage temp.:-20°C

solubility:Soluble to 100mM in DMSO and to 75mM in ethanol

form:White to off-white crystalline solid.

Stability:Stable. Combustible. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides. May absorb, and react with, carbon dioxide from the air.

 

 

Description   

Artemisinin is an antimalarial agent with anticancer activity. It is an iron(II) oxide-reactive endoperoxide that generates reactive oxygen species (ROS) upon cleavage of its endoperoxide bridge. It reduces the growth of various P. falciparum strains in vitro (IC50s = 3.98-20.36 nM) and reduces parasitemia in mice infected with P. falciparum with a curative dose (CD50) value of 140 mg/kg. It also reduces P. berghei infection in mice (ED50 = 5.6 mg/kg per day). Artemisinin (100-400 μM) induces cell cycle arrest in the G0/G1 phase and apoptosis and inhibits growth of SK-N-AS, BE(2)-C, SK-N-DZ, and SHEP1 neuroblastoma cells in a time- and concentration-dependent manner. It also suppresses BE(2)-C cell colony formation in a soft agar assay and reduces tumor growth in a BE(2)-C mouse xenograft model. Formulations containing artemisinin have been used in combination therapies for the treatment of malaria.

 

 


Company Profile Introduction

Wuhan Hao Rong Biotechnology Co., Ltd., located in East Lake high tech Development Zone, Wuhan, is a company specializing in the production and operation of chemical raw materials, flavors and fragrances, food additives, agrochemicals and other products. The company has first-class production equipment, advanced production technology, scientific management system, perfect detection means, and an excellent R & D team. The R & D center of the company has a technical team specialized in research and development, as well as a number of advanced detection, experiment and pilot equipment, and has established a good technical support relationship with a number of scientific research institutions, with strong technical force. The company has a wide range of products, in line with the quality of survival, service and development, customer-centric, integrity management philosophy, do our best to provide customers with quality and cheap raw materials. In addition, haorong also helps customers develop and implement customized system solutions. In these core areas of the chemical industry, haorong's core expertise covers chemicals and application technology, flexible asset management and customized services.

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  • Since: 2019-11-21
  • Address: Room1-3,floor 4,building 5,International enterprise center,Guanshan 2nd Road,Wuhan East Lake New Tec
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