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Postion:Product Catalog >AR antagonist 1
AR antagonist 1
  • AR antagonist 1

AR antagonist 1 NEW

Price $78 $181 $268
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: AR antagonist 1 CAS No.: 1818885-54-9
Purity: 99.07% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameAR antagonist 1
DescriptionAR antagonist 1 is a potent antagonist of the androgen receptor. It binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266.
In vitroAR antagonist 1 (compound 29) is the ligand for the target ligase of ARD-266, a highly potent VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. AR antagonist 1 exhibits micromolar binding affinity to its E3 ligase complex and can be effectively used in designing potent and efficient PROTAC degraders.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 60 mg/mL (215.22 mM)
KeywordsAR antagonist1 | Target Protein-binding Moiety | AR antagonist-1 | Inhibitor | AR antagonist 1 | LNCaP | Linker | Ligands for Target Protein for PROTAC | inhibit | cancer | Ligands for E3 Ligase | VCaP | PROTAC | tumor | E3 ligase-recruiting Moiety
Inhibitors RelatedLenalidomide-Br | Dehydroisoandrosterone 3-acetate | S-23 | Lenalidomide | Flutamide
Related Compound LibrariesNuclear Receptor Compound Library | Bioactive Compound Library | Anti-Prostate Cancer Compound Library | NO PAINS Compound Library | Endocrinology-Hormone Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Transcription Factor-Targeted Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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