Apraclonidine NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Apraclonidine | CAS No.: 66711-21-5 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Apraclonidine |
| Description | Apraclonidine (ALO 2145) is a selective α2 and weak α1 receptor agonist that effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine is a topical ophthalmic solution [1] [2]. |
| In vitro | Apraclonidine hydrochloride (ALO 2145) is more commonly used topically for glaucoma, as it penetrates the cornea and blood-brain barrier to a lesser extent and therefore has fewer adverse systemic effects [2]. |
| In vivo | Apraclonidine hydrochloride (ALO 2145) is effective in animal models of elevated IOP and human glaucoma. Its ocular hypotensive effects are typically due to reduced aqueous humor synthesis and vasoconstriction at anterior segment branches of the ophthalmic artery. Apraclonidine (1.15%, single instillation) inhibits 98% of PGE2-induced aqueous flare elevation [2] [3]. Animal Model: male rabbits [3]. Dosage: 1.15%. Administration: single instillation. Result: Inhibited PGE2-induced elevation of aqueous flare in pigmented rabbits. |
| Storage | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $30.00/2mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
| $1.10/1g |
VIP4Y
|
Shaanxi Dideu Medichem Co. Ltd
|
2021-05-25 | |
| $1.10/1g |
VIP4Y
|
Dideu Industries Group Limited
|
2021-09-16 | |
| $1.10/1g |
VIP4Y
|
Shaanxi Dideu Medichem Co. Ltd
|
2021-05-13 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY