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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Endocrinology & Hormones>Androgen Receptor Inhibitors>Apalutamide
Apalutamide
  • Apalutamide
  • Apalutamide
  • Apalutamide
  • Apalutamide
  • Apalutamide

Apalutamide

Price Get Latest Price
Package 25Kg/Bag
Min. Order: 2Kg/Bag
Supply Ability: 20 tons
Update Time: 2024-12-26

Product Details

Product Name: Apalutamide CAS No.: 956104-40-8
EC-No.: 807-449-9 Min. Order: 2Kg/Bag
Purity: 0.99 Supply Ability: 20 tons
Release date: 2024/12/26

Product Information

Product name

Apalutamide / ARN-509

CAS No.

956104-40-8

Molecular Formula

C21H15F4N5O2S

Molecular Weight

477.442

Quality Standard

99% up by HPLC

Appearance

White powder

COA of Apalutamide

ITEMS

SPECIFICATION

RESULT

Appearance

White powder

Conforms

Solubility

Soluble in water or 1% acetic acid at a

concentration of ≥1mg/ml to give a clear,

colorless solution

Conforms

Related Substance

(by HPLC)

Total Impurities ≤ 1.0%

0.17%

Single impurity ≤ 0.2%

0.02%

Loss on drying

≤ 0.5%

0.3%

Assay (by HPLC)

99.0103.0%

99.8%%

Conclusion

It meets the enterprise standard.

Usage

Function of apalutamide

As a second-generation nonsteroidal androgen receptor inhibitory drugapalutamide can prevent the fusion of androgen and receptors, and block the transfer of AR to the nucleus of cancer cells. In addition, apalutamide can also control androgen and promote the growth of cancer cells.


The safety and efficacy of apalutamide are based on a randomized clinical trial of 1,207 patients with non-metastatic, castration-resistant prostate cancer. Patients in the trial received apalutamide or placebo. All patients also received hormone therapy, either with a gonadotropin-releasing hormone (GnRH) analog, or with surgery to lower the amount of testosterone in the body (surgical castration). Median metastasis-free survival was 40.5 months for patients taking apalutamide, compared with 16.2 months for patients taking placebo. From the above experiments, we can see that the effect of apalutamide in the treatment of prostate cancer is very significant.

Article illustration

Company Profile Introduction

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc.. We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland. Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients. In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA. We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.

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