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Postion:Product Catalog >Apafant
Apafant
  • Apafant

Apafant NEW

Price $113 $289 $428
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Apafant CAS No.: 105219-56-5
Supply Ability: 10g Release date: 2024/11/19

Product Introduction

Bioactivity

NameApafant
DescriptionApafant (WEB 2086) is a highly potent platelet activating factor (PAF) antagonist that blocks eosinophil activation and can be used to study experimental allergic conjunctivitis in guinea pigs.
In vivoGuinea pigs were actively sensitized and OA solution was instilled into the eyes of guinea pigs on Days 15 and 17 to elicit the allergic conjunctivitis. To examine the effects of Apafant on allergic conjunctivitis, Apafant ophthalmic solution was topically administered 0.1%, 1%, q.i.d. through Days 14 to 17. Compared to the controls (vehicle treatments), the animals treated with Apafant ophthalmic solution showed significantly reduced clinical symptoms (redness and edema) and itch-scratch responses in both the first and second antigen challenges. [1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 30 mg/mL(65.80 mM), Sonication is recommended.
KeywordsApafant
Inhibitors RelatedCV-6209 | Ginkgolide B | (-)-Denudatin B | Scutellarein tetramethyl ether | (Rac)-Modipafant | Niranthin | Zingiberen newsaponin | 48740 RP | Yangambin | Tulopafant | Rupatadine Fumarate | Ferulamide

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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