ANTIBACTERIAL PROTEIN LL-37 AMIDE (HUMAN) NEW
Price | Get Latest Price | ||
Package | 1KG | 5KG | 25KG |
Min. Order: | 1KG |
Supply Ability: | 20 T each week |
Update Time: | 2023-08-16 |
Product Details
Product Name: ANTIBACTERIAL PROTEIN LL-37 AMIDE (HUMAN) | CAS No.: 597562-32-8 |
Min. Order: 1KG | Purity: 98%~99% |
Supply Ability: 20 T each week | Release date: 2023/08/16 |
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Product Name: | ANTIBACTERIAL PROTEIN LL-37 AMIDE (HUMAN) |
Synonyms: | LL-37;ANTIBACTERIAL PROTEIN LL-37 AMIDE (HUMAN);H-LEU-LEU-GLY-ASP-PHE-PHE-ARG-LYS-SER-LYS-GLU-LYS-ILE-GLY-LYS-GLU-PHE-LYS-ARG-ILE-VAL-GLN-ARG-ILE-LYS-ASP-PHE-LEU-ARG-ASN-LEU-VAL-PRO-ARG-THR-GLU-SER-NH2;LL-37 Antibacterial Protein LL-37 aMide (huMan), LL37, CAMP;Antibacterial Protein LL-37 aMide (huMan), CAMP, LL37;LL-37 aMide;Anti-CAMP (66-80) antibody produced in rabbit;Anti-CAMP Cathelicidin anti-microbial peptide precursor |
CAS: | 597562-32-8 |
MF: | C205H341N61O52 |
MW: | 4492.27854 |
EINECS: | |
Product Categories: | 597562-32-8 |
Mol File: | 597562-32-8.mol |
ANTIBACTERIAL PROTEIN LL-37 AMIDE (HUMAN) Chemical Properties |
storage temp. | -20°C |
solubility | DMSO: Insoluble;Ethanol: 90 mg/mL (20.03 mM) |
form | buffered aqueous solution |
Water Solubility | Water: 90 mg/mL (20.03 mM) |
InChIKey | JATXYCFPJFQHBQ-XAMSXPGMSA-N |
ANTIBACTERIAL PROTEIN LL-37 AMIDE (HUMAN) Usage And Synthesis |
Description | LL-37, also known as hCAP18, belongs to the cathelicidins family of antimicrobial peptides that possess strong antimicrobial activity across multiple species. In humans, this is the only cathelicidin present, and it is produced in epithelial cells through the proteolytic cleavage of the hCAP-18 protein. In addition to its antimicrobial properties, LL-37 also plays a crucial role in regulating the immune system. It can inhibit inflammatory responses by suppressing the activation of TLR2 and TLR4, which recognize different components of bacterial cell walls. |
Chemical Properties | LL-37, a human antimicrobial peptide, is a white to off-white solid. This 37-residue peptide of cathelicidin origin is amphipathic and exhibits a broad spectrum of antimicrobial activity. |
Uses | LL-37 is a human antimicrobial peptide of the cathelicidin family and corresponds to the 134-170 segment of human cationic antimicrobial protein 18 (hCAP18). It plays an important role in the first line of defense against local infection and systemic invasion of pathogens at sites of inflammation and wounds. Cytotoxic to both bacterial and normal eukaryotic cells, LL-37 is significantly resistant to proteolytic degradation in solution. |
References | Singh et al., (2014) LL-37 Peptide Enhancement of Signal Transduction by Toll-like Receptor 3 Is Regulated by pH. J. Biol. Chem. 289(40) 27614 PMID: 25092290. Tripathi et al., (2014) LL-37 modulates human neutrophil responses to influenza A virus. J. Leukoc. Biol. 96(5) 931 PMID: 25082153. Roth et al., (2020). LL-37 fights SARS-CoV-2: The Vitamin D-Inducible Peptide LL-37 Inhibits Binding of SARS-CoV-2 Spike Protein to its Cellular Receptor Angiotensin Converting Enzyme 2 In Vitro. Preprint. doi: 10.1101/2020.12.02.408153 |
Company Profile Introduction
Shandong Huisheng Import & Export Co., Ltd. is located in Jinan city, Shandong Province, is a collection of domestic trade, international trade in one of the diversified services company. Our goal is to provide customers with high quality solutions and one-stop purchasing experience. At present, the company business scope involves five areas: Organic chemical raw materials, inorganic chemical raw materials, fine chemical raw materials, dangerous chemicals and green environmental protection chemical technology project promotion, and we has also established good relations of cooperation with several well-known enterprises and won the strong support of extensive trust from the new and old customers.
Products are widely used in automobile, household appliances, office supplies, mobile phone accessories, routers, food, medical and other fields. At present, our business covers 30 countries, and our customers mainly come from Australia, New Zealand, Canada, Germany, France, Poland, South Korea, Russia, Bangladesh, Vietnam, Kazakhstan, India, Ghana, Nigeria, South Africa, Egypt and other more than 30 countries.
The company has a sound quality management system and advanced professional equipment, with a positive attitude to meet the changing needs of customers. We take "quality products, quality service, competitive price, timely delivery" as the purpose, looking forward to greater cooperation with overseas customers on the basis of mutual benefit.
Our company provides a wide range of products to meet your various needs. Since its inception, the company has always adhered to the "quality first, customer first, reputation first" business policy, wholeheartedly meet the potential needs of our customers. Under the irresistible situation of economic globalization, our company is willing to cooperate sincerely with enterprises around the world to achieve a win-win situation.
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- Address: Room 202-9, Building 1, Evergrande Huafu, Dongying Road, Huaiyin District, Jinan City, Shandong Prov
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