Ampicillin NEW
| Price | $42 |
| Package | 1g |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Ampicillin | CAS No.: 69-53-4 |
| Purity: 99.59% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Ampicillin |
| Description | Ampicillin (Aminobenzylpenicillin) is a semi-synthetic penicillin belonging to the β-lactam group of antibiotics. Ampicillin has bactericidal activity against a wide range of Gram-positive and Gram-negative bacteria. |
| In vitro | METHODS: E. coli was treated with Ampicillin (0.1-10 μG/mL) for 6 h. Growth was measured using a Fisher Electrophotometer. RESULTS: No differences in E. coli growth were observed at concentrations of 0, 0.1, and 1.0 μG. 2.5, 5, and 10 μG concentrations of Ampicillin inhibited E. coli growth. [1] METHODS: Pharyngeal cancer cells Detroit-562 were treated with Ampicillin (10-100 μM) for 72 h. Cell viability was measured by MTT. RESULTS: The Ampicillin-treated groups at concentrations of 10, 25 and 50 μM showed higher cell viability than the control cells, with values of 112%, 107% and 106%, respectively. At concentrations of 75 and 100 μM, there was a slight but not significant decrease in cell viability with values of approximately 95% and 94%, respectively. [2] |
| In vivo | METHODS: To test the neuroprotective mechanism in a mouse model of transient total forebrain ischemia, Ampicillin (200 mg/kg) was injected intraperitoneally into C57BL/6 mice once a day for five days, and forebrain ischemia was induced 24 h after the last injection. RESULTS: Pretreatment with Ampicillin significantly attenuated neuronal damage in the CA1 subregion of the hippocampus, and Ampicillin may provide neuroprotection against cerebral ischemia/reperfusion injury by inducing GLT-1 protein and inhibiting MMP activity in the hippocampus of mice. [3] METHODS: To study the in vivo activity, Ampicillin (10-100 mg/kg) was administered by gavage to C57BL/6 mice once daily for two days. RESULTS: Exposure of mice to Ampicillin induced anxiety and colitis, and increased Aspergillus flora in the gut microbiota. [4] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 22.5 mg/mL (64.39 mM) 0.1 M NaOH : 25 mg/mL (71.55 mM), Sonication is recommended. |
| Keywords | Ampicillin | inhibit | Inhibitor | Antibiotic | D-alpha-Aminobenzylpenicillin | D-α-Aminobenzylpenicillin | Bacterial | D-a-Aminobenzylpenicillin |
| Related Compound Libraries | Bioactive Compound Library | Drug Repurposing Compound Library | Natural Product Library | Beta-Lactam Compound Library | Microbial Natural Product Library | Bioactive Compounds Library Max | Human Metabolite Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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