Amoxicillin NEW
| Price | $41 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Amoxicillin | CAS No.: 26787-78-0 |
| Purity: 99.92% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Amoxicillin |
| Description | Amoxicillin (Amoxycillin) binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Amoxicillin Anhydrous is the anhydrous form of a broad-spectrum, semisynthetic aminopenicillin antibiotic with bactericidal activity. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall and causes cell lysis. |
| In vivo | Amoxicillin was released more rapidly from phosphate buffer solution at pH 7.8 than from hydrochloric acid at pH 1.0. Amoxicillin was degraded in hydrochloric acid solution at 37°C, pH 1.0, indicating that Amoxicillin is less stable in acidic environment.Amoxicillin (≤8 mg/ml) inhibited 4 out of 15 strains.Amoxicillin (4 mg/ml) in combination with clavulanic acid (≤2 mg/ml) Amoxicillin (4 mg/ml) in combination with clavulanic acid (≤2 mg/ml) inhibited 14 out of 15 strains. In combination with cefotaxime (4 mg/ml), the IC50 of Amoxicillin on the strains was reduced from 0.5 mg/ml to 0.06 mg/ml, ranging from 0.01 to 0.25 mg/ml.Amoxicillin-treated cells secreted large amounts of IL-5, with little or no secretion of IL-4, TNFα, and interferon-gamma. Amoxicillin-specific T-cell clones did not exhibit drug-specific cytotoxicity, but were present to kill target cells at concanavalin A, suggesting that its primary capacity is cytolysis. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 68 mg/mL (186.1 mM) Ethanol : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | polypeptides | Inhibitor | inhibit | cell wall | Bacterial | antimicrobial | Antibiotic | Amoxicillin |
| Inhibitors Related | Neomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | EDTA copper(II) disodium salt | Dimethyl sulfoxide | Crystal Violet |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Drug-induced Liver Injury (DILI) Compound Library | Antibiotics Library | Drug Repurposing Compound Library | Beta-Lactam Compound Library | Anti-Bacterial Compound Library | FDA-Approved Drug Library | Immunology/Inflammation Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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