Amodiaquine NEW
| Price | $44 | $64 | $97 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-14 |
Product Details
| Product Name: Amodiaquine | CAS No.: 86-42-0 |
| Purity: 99.78% | Supply Ability: 10g |
| Release date: 2024/11/14 |
Product Introduction
Bioactivity
| 名稱(chēng) | Amodiaquine |
| 描述 | Amodiaquine is a synthetic aminoquinoline, used to treat malaria. |
| 體外活性 | Inflammatory responses are considered to play pivotal roles in the pathogenesis of intracerebral hemorrhage (ICH).?a nuclear receptor Nurr1 (NR4A2) was expressed prominently in microglia/macrophages and astrocytes in the perihematomal region in the striatum of mice after ICH.?Daily administration of a Nurr1 agonist amodiaquine (40 mg/kg, i.p.) from 3 h after ICH induction diminished perihematomal activation of microglia/macrophages and astrocytes.?Amodiaquine also suppressed ICH-induced mRNA expression of IL-1β, CCL2 and CXCL2, and ameliorated motor dysfunction of mice.?These results suggest that Nurr1 serves a novel target for ICH therapy. |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 71 mg/mL (199.52 mM) Methanol : 50 mg/mL (140.5 mM), Sonification is recommended. |
| 關(guān)鍵字 | CCL2 | Nurr1 | IL-1β | Histone Methyltransferase | Amodiaquin | inhibit | Inhibitor | anti-inflammatory | CXCL2 | neuroprotective | Parasite | Amodiaquine | antimalarial | N-methyltransferase |
| 相關(guān)產(chǎn)品 | Kaempferol | Hydroxychloroquine | Metronidazole | Nitazoxanide | Doxycycline | Chloroquine phosphate | Diethyltoluamide | Artemisinin | Benzyl benzoate | DL-Methionine |
| 相關(guān)庫(kù) | 抗寄生蟲(chóng)庫(kù) | 經(jīng)典已知活性庫(kù) | 兒童藥物庫(kù) | 表觀遺傳庫(kù) | 藥物功能重定位化合物庫(kù) | 抑制劑庫(kù) | FDA 上市藥物庫(kù) | 抗衰老化合物庫(kù) | 臨床期小分子藥物庫(kù) | 已知活性化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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