Amentoflavone NEW
| Price | $30 | $61 | $98 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-29 |
Product Details
| Product Name: Amentoflavone | CAS No.: 1617-53-4 |
| Purity: 99.22% | Supply Ability: 10g |
| Release date: 2025/05/29 |
Product Introduction
Bioactivity
| Name | Amentoflavone |
| Description | Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhibitor of human cathepsin B. It has antimalarial activity in trials significant affinities towards the Delta-1, kappa opioid receptors (as an antagonist) and binds to benzodiazepine receptors. Amentoflavone may be a potential lead for a new type of anti-inflammatory agents having the dual inhibitory activity of group II phospholipase A2 and cyclooxygenase. Amentoflavone and quercetin differentially exerted suppression of PGE2 biosynthesis via downregulation of COX-2/iNOS expression. |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 34 mg/mL (63.14 mM), Sonication is recommended. Chloroform, Dichloromethane, Ethyl Acetate : Soluble |
| Keywords | κ-opioid receptor | γ-Aminobutyric acid Receptor | U-87 MG cells | RSV | Respiratory syncytial virus | ReactiveOxygenSpecies | Reactive Oxygen Species | PLA2 | orally active | OpioidReceptor | Opioid Receptor | NF-?B | MCL1 | Inhibitor | inhibit | Gamma-aminobutyric acid Receptor | GABA Receptor | Fungal | CYP3A4 | CYP2C9 | COX-2 | COX | C-FLIP | Bacterial | Apoptosis | anti-inflammatory | antibacterial | Amentoflavone |
| Inhibitors Related | Neomycin sulfate | Stavudine | Cysteamine hydrochloride | Ampicillin sodium | Kanamycin sulfate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Doxycycline | Tributyrin | Naringin | Dimethyl sulfoxide | Alginic acid |
| Related Compound Libraries | Anti-Parasitic Compound Library | Traditional Chinese Medicine Monomer Library | Membrane Protein-targeted Compound Library | Miao medicine Compound Library | Anti-Viral Compound Library | Neuroprotective Compound Library | Anti-infective Natural Product Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-virus Traditional Chinese Medicine Monomer Library | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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