AM-8123 NEW
Price | $293 | $435 | $722 |
Package | 1mg | 2mg | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-20 |
Product Details
Product Name: AM-8123 | CAS No.: 2049973-02-4 |
Purity: 99.76% | Supply Ability: 10g |
Release date: 2024/11/20 |
Product Introduction
Bioactivity
Name | AM-8123 |
Description | AM-8123 is an orally available nonpeptide APJ agonist.AM-8123 reduces collagen load and improves cardiac function. AM-8123 ameliorates myocardial infarction in rats and can be used to study cardiovascular diseases such as heart failure. |
In vitro | AM-8123 inhibits histamine-stimulated cAMP production and promotes Gα protein activation[1]. |
In vivo | In 2-3-month-old Lewis rats, AM-8123 (100 mg/kg; oral administration) resulted in sustained improvement in systolic function. Additionally, echocardiography measurements showed that AM-8123 reduced end-diastolic volume (EDV) and end-systolic volume (ESV); however, no significant changes were observed by invasive pressure-volume conductance catheter measurements at the end of the study[1]. |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Keywords | AM8123 | AM-8123 | AM 8123 |
Inhibitors Related | ELA-11 (human) acetate(1784687-32-6 free base) | Apelin-12 acetate | Azelaprag | [Pyr1]-Apelin-13 | CMF019 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
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