Alvespimycin NEW
Price | $89 | $143 | $289 |
Package | 5mg | 10mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: Alvespimycin | CAS No.: 467214-20-6 |
Purity: 100% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | Alvespimycin |
Description | Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor that binds to Hsp90, exhibiting potential anticancer activity. |
In vitro | After treatment with vehicle control or 1 μM Alvespimycin (17-DMAG) for 24 hours, CLL patient cells showed that Alvespimycin downregulated NF-κB signaling through IKKα and IKKβ[2]. |
In vivo | Treatment with vehicle (DMSO) or Alvespimycin(17-DMAG)(10 mg/kg) significantly prolonged the survival time of TCL1-SCID model mice[2]. |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 80 mg/mL (129.71 mM), Sonication is recommended. |
Keywords | Alvespimycin |
Inhibitors Related | Ethoxyquin | SNX0723 | Tamoxifen | SNX2112 | Teprenone | Elesclomol | Rifabutin | Palmitic acid | Paeoniflorin | Tamoxifen Citrate |
Related Compound Libraries | Bioactive Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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