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Postion:Product Catalog >ALSTERPAULLONE
ALSTERPAULLONE
  • ALSTERPAULLONE

ALSTERPAULLONE NEW

Price $53 $118 $193
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: ALSTERPAULLONE CAS No.: 237430-03-4
Purity: 99.39% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameALSTERPAULLONE
DescriptionAlsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing Effec
In vitroAlsterpaullone inhibited HeLa cells in a time-dependent (0-72 h) and dose-dependent (0-30 μ M) manner.?In the presence of alsterpaullone, HeLa cells were arrested in G2/M prior to undergoing apoptosis via a mechanism that is involved in the regulation of various antiapoptotic genes, DNA-repair, transcription, and cell cycle progression.?Compared to controls, alsterpaullone effectively prevented HeLa cells from entering S-phase.?These potential therapeutic efficacies could be correlated with the activation of caspase-3[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 12 mg/mL (40.92 mM)
KeywordsCDK5 | GSK-3 | p35 | ALSTERPAULLONE | NSC-705701 | 9-Nitropaullone | NSC705701 | Glycogen synthase kinase-3 | cyclin E | Glycogen synthase kinase 3 | Cyclin dependent kinase | inhibit | NSC 705701 | antitumor | CDK2 | cyclin A | cyclin B | Inhibitor | CDK | Apoptosis | CDK1 | neurodegenerative
Inhibitors RelatedStavudine | 5-Fluorouracil | Acetylcysteine | Kaempferol | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | Dextran sulfate sodium salt (MW 4500-5500) | Metronidazole | Sorafenib | Tributyrin | Lidocaine hydrochloride
Related Compound LibrariesPI3K-AKT-mTOR Compound Library | Reprogramming Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Inhibitor Library | Neuroprotective Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Recommended supplier

Product name Price   Suppliers Update time
$1980.00/50mg
VIP1Y
TargetMol Chemicals Inc.
2024-10-22
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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