Product Details
Product Name:
AL 8697 |
CAS No.:
1057394-06-5 |
Purity:
99.26% |
Supply Ability:
10g |
Release date:
2024/11/19 |
Product Introduction
Bioactivity
Name | AL 8697 |
Description | AL 8697 is a selective p38α MAPK inhibitor (IC50 = 6 nM) with 14-fold selectivity over p38β (IC50 = 82 nM) and 300-fold selectivity over a panel of 91 kinases. AL 8697 has anti-inflammatory activity. |
In vivo | In male Wistar rats, AL 8697 (1, 3, 10, 30 mg/kg; p.o.) decreases the oedema in right and left paws in a dose-dependent manner thereby causing a larger improvement in the contralateral un-injected paw[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 95 mg/mL (236.08 mM), Sonication is recommended.
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Keywords | inhibit | AL8697 | p38 MAPK | AL-8697 | Autophagy | Inhibitor | AL 8697 |
Inhibitors Related | Adezmapimod | Doramapimod | Dihydrocaffeic acid | VX-702 | Bakuchiol | p38α inhibitor 3 | SB 202190 | (-)-Bornyl acetate | MW-150 | Allicin | (E)-Ferulic acid methyl ester | p38-α MAPK-IN-1 |
Related Compound Libraries | Anti-Colorectal Cancer Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Kinase Inhibitor Library | Pyroptosis Compound Library | Inhibitor Library | Anti-Prostate Cancer Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Liver Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
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