Akt3 degrader 1 NEW
Price | $195 | $483 | $692 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-20 |
Product Details
Product Name: Akt3 degrader 1 | CAS No.: 2836342-69-7 |
Purity: 99.14% | Supply Ability: 10g |
Release date: 2024/11/20 |
Product Introduction
Bioactivity
Name | Akt3 degrader 1 |
Description | Akt3 degrader 1 is a specific Akt3 degrader with anticancer and antiproliferative activity that inhibits tumor growth in mice.Akt3 degrader 1 is used in the study of non-small cell lung cancer and pancreatic cancer. |
In vitro | In H1975OR cells, Akt3 degrader 1 ( 0.001-100 μM ; 24 h ) could inhibit the growth of H1975OR cells with an IC50 of 0.972 μM[1]. |
In vivo | In NOD-SCID-IL2Rg-/- ( NSI ) mice ( H1975OR xenograft model ), Akt3 degrader 1 ( 10,20 mg/kg ; intraperitoneal administration ; every 3 days for 5 weeks ) can Inhibited tumor growth without causing obvious body weight loss or other signs of toxicity[1]. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Inhibitors Related | Ethyl gallate | Oridonin | Capivasertib | SKLB-163 | Scutellarin | Artemisinin | Honokiol | 2,3-Butanediol | MK-2206 dihydrochloride | AKT Kinase Inhibitor |
Related Compound Libraries | Bioactive Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
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