Product Details
| Product Name:
AkaLumine |
CAS No.:
1176235-08-7 |
| Supply Ability:
10g |
Release date:
2024/11/11 |
Product Introduction
Bioactivity
| 名稱(chēng) | AkaLumine |
| 描述 | AkaLumine (Aka Lumine) is a firefly luciferin analog that is a luciferase substrate that binds to Abeta aggregates and plaques.AkaLumine is used for in vivo optical imaging. |
| 體外活性 | In LLC/luc and MDA-MB-231/Luc cells treated with AkaLumine, the signal began to peak at a lower concentration of 2.5 μM. In contrast, bioluminescence produced by D-luciferin and CycLuc1 continued to rise with increasing concentration and did not reach a significant saturation point even at the highest concentration of 250 μM. [1] |
| 體內(nèi)活性 | In a time course of bioluminescence production in vivo, AkaLumine displayed a stable glow-type reaction at various injection doses and its bioluminescence production remained elevated longer at the higher concentrations; this temporally more stable bioluminescence production may be beneficial for acquiring images without influence of acquisition time. Furthermore, AkaLumine has a relatively longer half-life (～40?min) in serum. These results suggest that AkaLumine would be a suitable substrate for in vivo imaging. [1] |
| 存儲(chǔ)條件 | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 關(guān)鍵字 | AkaLumine |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Price |
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Suppliers |
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$93.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 |
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United States