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Postion:Product Catalog >AH-7614
AH-7614
  • AH-7614

AH-7614 NEW

Price $47 $83 $183
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-05-30

Product Details

Product Name: AH-7614 CAS No.: 6326-06-3
Purity: 98.05% Supply Ability: 10g
Release date: 2025/05/30

Product Introduction

Bioactivity

NameAH-7614
DescriptionAH-7614 (AH 7614) is a selective and potent free fatty acid receptor 4 (FFA4/GPR120) antagonist.
In vitroAH7614 (0.063, 0.25, and 1μM) blocked linoleic acid and GSK137647A-induced intracellular calcium increase in U2OS osteosarcoma cells expressing the FFA4 receptor. In addition, the increase of glucose-stimulated insulin secretion by GSK137647A (50 μM) was abolished in the presence of the selective FFA4 antagonist AH7614 (100 μM) in the MIN6 mouse insulinoma cell line. Moreover, AH7614 (100 μM) blocked GSK137647A (100μM)-mediated a modest increase of GLP-1 secretion in the NCIH716 cells.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (142.28 mM), Sonication is recommended.
Ethanol : Insoluble
H2O : Insoluble
Keywordsnegative | NAM | linoleic | Inhibitor | inhibit | GPR120 | Free Fatty Acid Receptor | FFAR | FFA4 | allosteric | AH-7614 | AH7614 | acid
Inhibitors RelatedVincamine | Monomethyl fumarate | Questiomycin A | Azathioprine | CRTh2 antagonist 2 | Fezagepras sodium | Benzyl nicotinate | 1-methoxycyclopropanecarboxylic acid | TUG-1375 | CAY10595 | Timapiprant | NF-56-EJ40
Related Compound LibrariesMembrane Protein-targeted Compound Library | Inhibitor Library | Endocrinology-Hormone Compound Library | NO PAINS Compound Library | GPCR Compound Library | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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