Adenosine NEW
| Price | $46 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-16 |
Product Details
| Product Name: Adenosine | CAS No.: 58-61-7 |
| Purity: 99.92% | Supply Ability: 10g |
| Release date: 2025/06/16 |
Product Introduction
Bioactivity
| Name | Adenosine |
| Description | Adenosine (D-Adenosine) is a natural product, a ribonucleoside consisting of adenine bound to ribose. Adenosine has vasodilatory, antiarrhythmic and analgesic effects. |
| In vitro | METHODS: Human prostate cancer cells DU-145, PC3 and LNcap-FGC-10 were treated with Adenosine (0.1-1000 μM) for 48 h. Cell viability was measured by MTT assay. RESULTS: Adenosine significantly reduced cell proliferation of DU-145, PC3 and LNcap-FGC10 cell lines in a dose-dependent manner. [1] METHODS: Human hepatocellular carcinoma cells HepG2 were treated with Adenosine (2 mM) for 6-24 h. The cell cycle was detected by Flow cytometry. RESULTS: Adenosine-induced inhibition of survival was attributed to the arrest of cell cycle progression. Adenosine significantly increased the percentage of G0/G1-phase cells and decreased the percentage of S-phase and G2/M-phase cells in HepG2 cells. [2] |
| In vivo | METHODS: To investigate the antidepressant-like effects, Adenosine (1-10 mg/kg) was intraperitoneally injected into mice and subjected to the forced swimming test (FST) and tail suspension test (TST). RESULTS: The immobilization time in the FST was shortened by intraperitoneal injection of Adenosine (5-10 mg/kg), and Adenosine (1-10 mg/kg) also produced antidepressant-like effects in the TST. [3] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | 5% DMSO+95% Saline : 1.05 mg/mL (3.93 mM), Solution. DMSO : 20 mg/mL (74.84 mM), Sonication is recommended. H2O : 2.7 mg/mL (10.1 mM), Sonication is recommended. 10% DMSO+90% Saline : 2 mg/mL (7.48 mM), Solution. |
| Keywords | vascular | regulation | platelet | NucleosideAntimetabolite | Nucleoside Antimetabolite/Analog | Nucleoside Antimetabolite | Nucleoside | neuronal | Inhibitor | inhibit | GPCR | EndogenousMetabolite | Endogenous Metabolite | endogenous | cell | blood | Autophagy | Apoptosis | Analog | aggregation | Adenosine |
| Inhibitors Related | Sucrose | Cysteamine hydrochloride | Hydroxychloroquine | Daidzein | Fumaric acid | Tributyrin | Ferulic Acid | Paeonol | Glycerol | Thymidine | Alginic acid | 3-Indoleacetic acid |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Bioactive Compound Library | Drug Repurposing Compound Library | Miao medicine Compound Library | Microbial Natural Product Library | Tobacco Monomer Library | FDA-Approved Drug Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Gut Microbial Metabolite Library | Heat-Clearing and Detoxifying Traditional Chinese Medicine Compound Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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