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Postion:Product Catalog >Biochemical Engineering>nucleic acid drugs>Adenosine
Adenosine
  • Adenosine

Adenosine NEW

Price $46
Package 500mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Adenosine CAS No.: 58-61-7
Purity: 99.92% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameAdenosine
DescriptionAdenosine (D-Adenosine) is a natural product, a ribonucleoside consisting of adenine bound to ribose. Adenosine has vasodilatory, antiarrhythmic and analgesic effects.
In vitroMETHODS: Human prostate cancer cells DU-145, PC3 and LNcap-FGC-10 were treated with Adenosine (0.1-1000 μM) for 48 h. Cell viability was measured by MTT assay. RESULTS: Adenosine significantly reduced cell proliferation of DU-145, PC3 and LNcap-FGC10 cell lines in a dose-dependent manner. [1] METHODS: Human hepatocellular carcinoma cells HepG2 were treated with Adenosine (2 mM) for 6-24 h. The cell cycle was detected by Flow cytometry. RESULTS: Adenosine-induced inhibition of survival was attributed to the arrest of cell cycle progression. Adenosine significantly increased the percentage of G0/G1-phase cells and decreased the percentage of S-phase and G2/M-phase cells in HepG2 cells. [2]
In vivoMETHODS: To investigate the antidepressant-like effects, Adenosine (1-10 mg/kg) was intraperitoneally injected into mice and subjected to the forced swimming test (FST) and tail suspension test (TST). RESULTS: The immobilization time in the FST was shortened by intraperitoneal injection of Adenosine (5-10 mg/kg), and Adenosine (1-10 mg/kg) also produced antidepressant-like effects in the TST. [3]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 20 mg/mL (75 mM)
H2O : 2.7 mg/mL (10 mM)
Keywordsneuronal | endogenous | regulation | Adenosine | Endogenous Metabolite | blood | aggregation | Nucleoside Antimetabolite/Analog | Apoptosis | Inhibitor | vascular | cell | GPCR | platelet | inhibit | Autophagy
Inhibitors RelatedSucrose | Hydroxychloroquine | Daidzein | Guanidine hydrochloride | Tributyrin | Ferulic Acid | Paeonol | Glycerol | Thymidine
Related Compound LibrariesAnti-Tumor Natural Product Library | Traditional Chinese Medicine Monomer Library | Alkaloid Natural Product Library | Natural Product Library | Microbial Natural Product Library | Natural Product Library for HTS | Anti-Cancer Approved Drug Library | Cosmetic Ingredient Compound Library | Gut Microbial Metabolite Library | Ancient Chinese Classical Formulas Compound Library

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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  • Since: 2011-01-07
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