ACT-678689 NEW
Price | $129 | $272 | $413 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: ACT-678689 | CAS No.: 1783256-96-1 |
Purity: 99.46% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | ACT-678689 |
Description | ACT-678689 (Compound Example 1.53.4) is a tryptophan hydroxylase (TPH) inhibitor with an IC50 of 8 nM[1]. |
In vitro | TPH consists of two isoforms, TPH1 and TPH2. TPH1 is primarily found in peripheral tissues, especially the enterochromaffin cells (EC) in the gut, and is vital for the synthesis of 5HT, which is stored in the circulating blood platelets[1]. Conversely, TPH2 is predominantly expressed in neuronal cell types within the central nervous system (CNS). |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 120 mg/mL (212.37 mM), Sonication is recommended. |
Keywords | Tryptophan Hydroxylase | Inhibitor | inhibit | ACT-678689 | ACT678689 | ACT 678689 |
Inhibitors Related | p-Ethynylphenylalanine | Mildronate | Tetrahydropapaverine hydrochloride | Casein | p-Fluoro-L-phenylalanine | Telotristat Etiprate | Ketoconazole | Bupicomide | Diethyl-pythiDC | Fenclonine | Nepicastat hydrochloride | Sapropterin dihydrochloride |
Related Compound Libraries | Bioactive Compound Library | Inhibitor Library | NO PAINS Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Fluorochemical Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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