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Postion:Product Catalog >API>Specialty drugs>Dermatology drugs>Acitretin
Acitretin
  • Acitretin
  • Acitretin
  • Acitretin
  • Acitretin

Acitretin NEW

Price $100 $95 $90
Package 1kg 25kg 1000kg
Min. Order: 1kg
Supply Ability: 100Tons
Update Time: 2024-12-12

Product Details

Product Name: Acitretin CAS No.: 55079-83-9
EC-No.: 259-474-4 Min. Order: 1kg
Purity: 99% Supply Ability: 100Tons
Release date: 2024/12/12

Acitretin is a second generation retinoid. It is taken orally, and is typically used for psoriasis. It is a metabolite of etretinate, which was used prior to the introduction of acitretin. They induce keratinocyte differentiation and reduce epidermal hyperplasia.

Acitretin is the least toxic systemic treatment for psoriasis. It is an oral retinoid of choice used in the treatment of severe resistant psoriasis. It binds to nuclear receptors that regulate gene transcription.

Acitretin was discontinued because it had a narrow therapeutic index as well as a long elimination half-life (t1/2 =120 days), making dosing difficult. In contrast, acitretin's half-life is approximately 2 days.


Acitretin is an oral retinoid used in the treatment of severe resistant psoriasis.Because of the potential for problems and severe side effects it is generally used in only very severe cases of psoriasis that have been unresponsive to other treatments.

It binds to nuclear receptors that regulates gene transcription. They induce keratinocyte differentiation and reduce epidermal hyperplasia, leading to the slowing of cell reproduction. Acitretin is readily absorbed and widely distributed after oral administration. A therapeutic effect occurs after 2 to 4 weeks or longer.

Patients that have received the medication are advised against giving blood for at least 3 years due to the risk of birth defects

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Company Profile Introduction

-.Hebei Dangtong Biological Technology Co.,LTD founded in April 2004,has more than 960employees. Headquartered in Luquan District, Shijiazhuang city,Hebei Province, weare a professional manufacturer of alkaline dyes, chemical raw materials, foodadditives and pharmaceutical intermediates. The company has 3 production bases. Respectively in Hebei, Inner Mongolia, Yunnan three factory bases. It has two research centers and three laboratories specializing in the development of new products and the optimization of existing products. Committed to providing higher quality products and services to meet customer personalized needs. In terms of production, the company insists on integrated production, supplying main raw materials by itself, and laying out lean factories to ensure sustainable and stable supply.

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  • Since: 2021-05-08
  • Address: Room 10-0-1001, Chunbei District, Shunde North Road, Xiangdu District, Xingtai city, Hebei Province
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