Acalabrutinib NEW
Price | Get Latest Price | ||
Package | 1Kg/Bag | 25Kg/Bag | 100Kg/Bag |
Min. Order: | 1Kg/Bag |
Supply Ability: | 20 tons |
Update Time: | 2024-12-23 |
Product Details
Product Name: Acalabrutinib | CAS No.: 1420477-60-6 |
EC-No.: 814-272-0 | Min. Order: 1Kg/Bag |
Purity: 0.99 | Supply Ability: 20 tons |
Release date: 2024/12/23 |
Product Information
Name | Acalabrutinib |
Other names | Acalabrutinib 1420477-60-6 ACP-196 Calquence Acalabrutinib (ACP-196) |
CAS number | 1420477-60-6 |
Molecular Formula | C26H23N7O2 |
Molecular Weight | 465.51 |
EINECS | 814-272-0 |
Acalabrutinib is a novel anti-cancer drug and a second generation Bruton's tyrosine kinase (BTK) inhibitor developed by Acerta Pharma. It is more potent and selective (fewer side-effects) than ibrutinib, the first-in-class BTK inhibitor. In October 2017, the Food and Drug Administration approved the drug for treatment of mantle cell lymphoma in patients who had previously been treated with another therapy.
Application
Drug Indication | Acalabrutinib is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, acalabrutinib inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents both B-cell activation and BTK-mediated activation of downstream survival pathways. This leads to an inhibition of the growth of malignant B cells that overexpress BTK. BTK, a member of the src-related BTK/Tec family of cytoplasmic tyrosine kinases, is overexpressed in B-cell malignancies; it plays an important role in B lymphocyte development, activation, signaling, proliferation and survival. |
Formulations/Preparations | Tablet Powder for Suspension Tablet, Chewable Tablet, Extended Release Capsule |
Company Information
Company Profile Introduction
Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc..
We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland.
Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients.
In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA.
We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.
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- Since: 1996-07-16
- Address: Fujian China ,16F, Huicheng Comm. Complex, 839 Xiahe RD.
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